SIRT1(phospho S47) Monoclonal Antibody

Applications

  • WB
  • IF(ICC)
  • IHC

Reactivity

  • Human
Overview
Catalog # bsm-54566R
Product Name SIRT1(phospho S47) Monoclonal Antibody
Applications WB, IF(ICC), IHC
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Synthetic phospho-Peptide corresponding to residues surrounding Ser47 of human SIRT1
Modification Site Ser47
Clonality Monoclonal
Clone # 8B1
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.05% Sodium Azide and 40% Glycerol.
Storage Condition Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
Gene ID 23411
Swiss Prot Q96EB6
Subcellular location Cytoplasm, Nucleus
Synonyms 75SirT1 antibody, hSIR2 antibody, hSIRT1 antibody, HST2, S. cerevisiae, homolog of antibody, NAD dependent deacetylase sirtuin 1 antibody, NAD dependent protein deacetylase sirtuin 1 antibody, OTTHUMP00000198111 antibody, OTTHUMP00000198112 antibody, Regulatory protein SIR2 homolog 1 antibody, SIR1_HUMAN antibody, SIR2 antibody, SIR2 like 1 antibody, SIR2 like protein 1 antibody, SIR2, S.cerevisiae, homolog-like 1 antibody, SIR2-like protein 1 antibody, SIR2ALPHA antibody, SIR2L1 antibody, Sirt1 antibody, SirtT1 75 kDa fragment antibody, Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) antibody, Sirtuin 1 antibody, Sirtuin type 1 antibody
Background This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
Application Dilution
WB 1:300-5000
IF(ICC) 1:50-200
IHC