Phospho-EGFR(Y1068) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54587R-100uL |
| Product Name | Phospho-EGFR(Y1068) Monoclonal Antibody |
| Applications |
WB
IF(ICC)
IP
FCM
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Synthetic phospho-Peptide corresponding to residues surrounding Tyr1068 of human EGFR. |
| Modification Site | Tyr1068 |
| Clonality | Monoclonal |
| Clone # | 1H2 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 1956 |
| Swiss Prot | P00533 |
| Subcellular location | Nucleus, Secreted, Cell membrane, Endosome, Endoplasmic reticulum membrane, Golgi apparatus membrane, Nucleus membrane |
| Synonyms | Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody, Cell growth inhibiting protein 40 antibody, Cell proliferation inducing protein 61 antibody, EGF R antibody, EGFR antibody, EGFR_HUMAN antibody, Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) antibody, Epidermal growth factor receptor (erythroblastic leukemia viral (v erb b) oncogene homolog avian) antibody, Epidermal growth factor receptor antibody, erb-b2 receptor tyrosine kinase 1 antibody, ERBB antibody, ERBB1 antibody, Errp antibody, HER1 antibody, mENA antibody, NISBD2 antibody, Oncogen ERBB antibody, PIG61 antibody, Proto-oncogene c-ErbB-1 antibody, Receptor tyrosine protein kinase ErbB 1 antibody, Receptor tyrosine-protein kinase ErbB-1 antibody, SA7 antibody, Species antigen 7 antibody, Urogastrone antibody, v-erb-b Avian erythroblastic leukemia viral oncogen homolog antibody, wa2 antibody, Wa5 antibody |
| Background | The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(ICC) | 1:50-200 |
| IP | 1-2ug |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is Phospho-EGFR(Y1068) Monoclonal Antibody (bsm-54587R) validated for, and at what dilution?
bsm-54587R is validated for WB (1:300-5000); IF(ICC) (1:50-200); IP (1-2ug); FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Phospho-EGFR(Y1068) Monoclonal Antibody (bsm-54587R) react with?
Tested reactivity: Human.
How should bsm-54587R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Phospho-EGFR(Y1068) Monoclonal Antibody (bsm-54587R)?
Synthetic phospho-Peptide corresponding to residues surrounding Tyr1068 of human EGFR.