AP-A Monoclonal Antibody


  • WB
  • IHC-P
  • IHC


  • Human
Catalog # bsm-54646R
Product Name AP-A Monoclonal Antibody
Applications WB, IHC-P, IHC
Reactivity Human
Conjugation Unconjugated
Host Rabbit
Source Synthetic Peptide within Human AP-A.
Clonality Monoclonal
Clone # 11B3
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Gene ID 2028
Swiss Prot Q07075
Subcellular location Cell membrane, Membrane
Synonyms Aminopeptidase A antibody, AMPE_HUMAN antibody, AP-A antibody, APA antibody, bp-1 antibody, bp1 antibody, CD249 antibody, Differentiation antigen gp160 antibody, EAP antibody, Enpep antibody, Glutamyl aminopeptidase (aminopeptidase A) antibody, Glutamyl aminopeptidase antibody, Gp160 antibody, Ly51 antibody
Background Aminopeptidase A, also designated APA, gp160 human kidney differentiation antigen, glutamyl aminopeptidase, or enpep, is a differentiation-related kidney glycoprotein. As a cell surface, zinc-dependent metalloprotease, Aminopepti-dase A specifically cleaves amino-terminal acidic residues from peptide substrates such as Angiotensin II. APA is expressed on the surface of epithelial cells of the glomerulus and proximal tubule cells of the human nephron, where it may mediate the constitutive trafficking of Glut4-containing vesicles. These Glut4-containing vesicles are tissue-specific secretory-like microsomal structures that mediate insulin-dependent translocation of GLUT4 to the cell surface in fat and muscle cells. Mutations in the gp160/APA gene, including loss of protein expression or enzymatic activity, occur in 20% of primary clear cell renal carcinomas.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400