Thyroglobulin Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54657R-100uL |
| Product Name | Thyroglobulin Monoclonal Antibody |
| Applications |
WB
IHC
IHC-P
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Recombinant protein within C-terminal human Thyroglobulin. |
| Clonality | Monoclonal |
| Clone # | 2H4 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 7038 |
| Swiss Prot | P01266 |
| Subcellular location | Secreted |
| Synonyms | AITD 3 antibody, AITD3 antibody, hTG antibody, TDH3 antibody, Tg antibody, TGN antibody, THYG_HUMAN antibody, Thyroglobulin antibody |
| Background | Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC | 1:50-200 |
| IHC-P | 1:200-400 |
Frequently asked questions
Which applications is Thyroglobulin Monoclonal Antibody (bsm-54657R) validated for, and at what dilution?
bsm-54657R is validated for WB (1:300-5000); IHC (1:50-200); IHC-P (1:200-400). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Thyroglobulin Monoclonal Antibody (bsm-54657R) react with?
Tested reactivity: Human.
How should bsm-54657R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Thyroglobulin Monoclonal Antibody (bsm-54657R)?
Recombinant protein within C-terminal human Thyroglobulin.