Thyroglobulin Monoclonal Antibody

Applications

  • WB
  • IHC-P
  • IHC

Reactivity

  • Human
Overview
Catalog # bsm-54657R
Product Name Thyroglobulin Monoclonal Antibody
Applications WB, IHC-P, IHC
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant protein within C-terminal human Thyroglobulin.
Clonality Monoclonal
Clone # 2H4
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 7038
Swiss Prot P01266
Subcellular location Secreted
Synonyms AITD 3 antibody, AITD3 antibody, hTG antibody, TDH3 antibody, Tg antibody, TGN antibody, THYG_HUMAN antibody, Thyroglobulin antibody
Background Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC