DBF4 Monoclonal Antibody
Applications
Reactivity
Overview | |
Catalog # | bsm-54705R |
Product Name | DBF4 Monoclonal Antibody |
Applications | WB, FCM |
Reactivity | Human, Mouse |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | Synthetic Peptide within N-terminal human DBF4. |
Clonality | Monoclonal |
Clone # | 5H0 |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Storage Condition | Store at -20°C for 12 months. |
Target | |
Gene ID | 10926 |
Swiss Prot | Q9UBU7 |
Subcellular location | Nucleus |
Synonyms | Activator of S phase kinase antibody, ASK antibody, CHIF antibody, Chiffon homolog A antibody, DBF4 antibody, DBF4 homolog (S. cerevisiae) antibody, DBF4 homolog antibody, DBF4 type zinc finger containing protein 1 antibody, DBF4 zinc finger A antibody, DBF4 zinc finger antibody, DBF4, S. cerevisiae, homolog of antibody, DBF4-type zinc finger-containing protein 1 antibody, DBF4A antibody, DBF4A_HUMAN antibody, Dumbbell former 4, S. cerevisiae, homolog of antibody, OTTHUMP00000161661 antibody, Protein DBF4 homolog A antibody, ZDBF1 antibody, Zinc finger, DBF-type containing 1 antibody |
Background | Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. Tissue specificity: Highly expressed in testis and thymus. Expressed also in most cancer cells lines. |
Application Dilution | |
WB | 1:300-5000 |
FCM | 1:20-100 |