Arg2 Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54747R |
| Product Name | Arg2 Monoclonal Antibody |
| Applications |
WB
FCM
IHC-P
IF(ICC)
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Synthetic Peptide within C-terminal Human Arg2. |
| Clonality | Monoclonal |
| Clone # | 9H7 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 384 |
| Swiss Prot | P78540 |
| Subcellular location | Mitochondrion |
| Synonyms | ARG2 antibody, ARGI2_HUMAN antibody, Arginase II mitochondrial antibody, Arginase type II antibody, Arginase-2 antibody, arginase-2, mitochondrial antibody, Kidney arginase antibody, Kidney type arginase antibody, Kidney-type arginase antibody, L arginine amidinohydrolase antibody, L arginine ureahydrolase antibody, mitochondrial antibody, Non hepatic arginase antibody, Non-hepatic arginase antibody, Nonhepatic arginase antibody, Type II arginase antibody |
| Background | Arginase I (also designated liver-type arginase), which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea (1). The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster (2-4). Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location (5,6). Specifically, arginase II localizes to the mitochondria (5,6). Arginase II is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike arginase I, is not expressed in liver (5,6). The human arginase II gene, which maps to chromosome 14q24.1, encodes a 354 amino acid protein (3,5-7). In addition, arginase II contains a putative amino-terminal mitochondrial localization sequence (5,6). |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |
| IHC-P | 1:200-400 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is Arg2 Monoclonal Antibody (bsm-54747R) validated for, and at what dilution?
bsm-54747R is validated for WB (1:300-5000); FCM (1:20-100); IHC-P (1:200-400); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Arg2 Monoclonal Antibody (bsm-54747R) react with?
Tested reactivity: Human.
How should bsm-54747R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Arg2 Monoclonal Antibody (bsm-54747R)?
Synthetic Peptide within C-terminal Human Arg2.