CTNNA3 Monoclonal Antibody

$Paraformaldehyde-fixed, paraffin embedded Mouse heart; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37\u00b0C for 30min; Antibody incubation with CTNNA3 Monoclonal Antibody, Unconjugated (bsm-54761R) at 1:50 for 30 minutes at room temperature, DAB staining.$

Paraformaldehyde-fixed, paraffin embedded Mouse heart; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37\u00b0C for 30min; Antibody incubation with CTNNA3 Monoclonal Antibody, Unconjugated (bsm-54761R) at 1:50 for 30 minutes at room temperature, DAB staining.

$Paraformaldehyde-fixed, paraffin embedded Rat heart; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37\u00b0C for 30min; Antibody incubation with CTNNA3 Monoclonal Antibody, Unconjugated (bsm-54761R) at 1:50 for 30 minutes at room temperature, DAB staining.$

Paraformaldehyde-fixed, paraffin embedded Rat heart; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37\u00b0C for 30min; Antibody incubation with CTNNA3 Monoclonal Antibody, Unconjugated (bsm-54761R) at 1:50 for 30 minutes at room temperature, DAB staining.

Applications

WB
IHC-P

Reactivity

Human
Mouse
Rat

Overview
Catalog #	bsm-54761R
Product Name	CTNNA3 Monoclonal Antibody
Applications	WB, IHC-P
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Recombinant fragment within C-terminal Human CTNNA3.
Clonality	Monoclonal
Clone #	3H55
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	29119
Swiss Prot	Q9UI47
Subcellular location	Cytoskeleton
Synonyms	4930429L08Rik antibody, 4933408A16 antibody, Alpha catenin like protein antibody, Alpha T catenin antibody, Alpha T-catenin antibody, Cadherin associated protein antibody, Cadherin-associated protein antibody, Catenin alpha 3 antibody, Catenin alpha-3 antibody, Catna3 antibody, CTNA3_HUMAN antibody, CTNNA3 antibody, MGC26194 antibody, MGC75041 antibody, OTTHUMP00000019684 antibody, OTTMUSP00000028119 antibody, OTTMUSP00000028120 antibody, RP11-433J16.1 antibody, VR22 antibody
Background	The catenins are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. alpha T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantally expressed in cardiomyocytes and in the peritubular myoid cells of the testis. alpha T-catenin binds to alpha E-catenin as well as to beta-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for alpha-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer's disease (LOAD) as well as to dilated cardiomyopathy.
Application Dilution
WB	1:300-5000
IHC-P	1:200-400

Applications

Reactivity

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