GP1BA Recombinant Antibody, APC-Cy5.5 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-60017r-apc-cy55-100ul |
| Product Name | GP1BA Recombinant Antibody, APC-Cy5.5 Conjugated |
| Applications |
WB
IF(IHC-P)
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | APC-Cy5.5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human CD42b |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | 1mg/ml |
| Purification | purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 2811 |
| Swiss Prot | P07359 |
| Subcellular location | Cell membrane |
| Synonyms | Antigen CD42b alpha; BSS; CD 42b; CD42b alpha; CD42b antigen; GLYCOCALICIN; Glycoprotein Ib (platelet) alpha polypeptide; Glycoprotein Ibalpha; GP Ib alpha; GP1B; GP1BA; GPIb alpha; MGC34595; Platelet glycoprotein Ib alpha chain; Platelet glycoprotein Ib alpha polypeptide; Platelet membrane glycoprotein 1b alpha subunit. |
| Background | Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010]. |
| Application Dilution | |
| WB | 1:500-2000 |
| IF(IHC-P) | |
Frequently asked questions
Which applications is GP1BA Recombinant Antibody, APC-Cy5.5 Conjugated (BSM-60017R-APC-CY5-5) validated for, and at what dilution?
BSM-60017R-APC-CY5-5 is validated for WB (1:500-2000); IF(IHC-P). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does GP1BA Recombinant Antibody, APC-Cy5.5 Conjugated (BSM-60017R-APC-CY5-5) react with?
Tested reactivity: Human, Mouse, Rat.
How should BSM-60017R-APC-CY5-5 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise GP1BA Recombinant Antibody, APC-Cy5.5 Conjugated (BSM-60017R-APC-CY5-5)?
KLH conjugated synthetic peptide derived from human CD42b
What are the excitation and emission wavelengths of the APC-Cy5.5 conjugate (BSM-60017R-APC-CY5-5)?
APC-Cy5.5 on BSM-60017R-APC-CY5-5: excitation / emission 650nm/694nm.