CD2 Recombinant Antibody, APC-Cy5.5 Conjugated

Applications

  • IF

Reactivity

  • Human
Overview
Catalog # bsm-60313r-apc-cy55-100l
Product Name CD2 Recombinant Antibody, APC-Cy5.5 Conjugated
Applications IF
Reactivity Human
Specifications
Conjugation APC-Cy5.5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CD2
Clonality Recombinant
Isotype IgG
Concentration 1mg/ml
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 914
Swiss Prot P06729
Subcellular location Cell membrane
Synonyms T-cell surface antigen CD2; CD 2; CD2 antigen; CD2 molecule; LFA2; LFA3 receptor; Lymphocyte function antigen 2; p50; Rosette receptor; Sheep erythrocyte receptor; Sheep red blood cell receptor; SRBC; T cell surface antigen CD2; T cell surface antigen T11/Leu 5; T11; CD2_HUMAN.
Background CD2 is a surface antigen of the human T lymphocyte lineage that is expressed on all peripheral blood T cells. It is one of the earliest T cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes.
CD2 interacts with lymphocyte function associated antigen (LFA3) and CD48/BCM1 to mediate adhesion between T cells and other cell types. CD2 is implicated in the triggering of T cells, the cytoplasmic domain is implicated in the signaling function. It is useful for the identification of lymphomas and leukaemias of T cell origin.
Application Dilution
IF 1:200-1000