TMEM119 Monoclonal Antibody

$25 ug total protein per lane of various lysates (see on figure) probed with TMEM119 monoclonal antibody, unconjugated (bsm-60881M) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.$

25 ug total protein per lane of various lysates (see on figure) probed with TMEM119 monoclonal antibody, unconjugated (bsm-60881M) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

Applications

Reactivity

Mouse

Predicted Reactivity

Human
Rat

Overview
Catalog #	bsm-60881m
Product Name	TMEM119 Monoclonal Antibody
Applications	WB
Reactivity	Mouse
Predicted Reactivity	Human, Rat
Specifications
Conjugation	Unconjugated
Host	Mouse
Source	KLH conjugated synthetic peptide derived from human TMEM119
Clonality	Monoclonal
Isotype	IgG3/Kappa
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	338773
Subcellular location	Cytoplasm, Cell membrane
Synonyms	Transmembrane protein 119; TM119_HUMAN; OBIF; Osteoblast Induction Factor
Background	Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts (PubMed:20025746). May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Up-regulates the expression of ATF4, a transcription factor which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation (By similarity).
Application Dilution
WB	1:500-2000