STAT5A Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-60899r |
| Product Name | STAT5A Recombinant Antibody |
| Applications |
IHC-P
IHC-F
IF(IHC-P)
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human STAT5 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 6776 |
| Swiss Prot | P42229 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | signal transducers and activators of transduction 5; MGF; Signal Transducer and Activator of Transcription 5A; STAT 5; STAT 5A; STAT 5B; STAT5A; STAT5B; Transcription factor STAT5A; STA5B_HUMAN; STA5A_HUMAN. |
| Background | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008] |
| Application Dilution | |
| IHC-P | 1:100-500 |
| IHC-F | IHC-F1:100-500 |
| IF(IHC-P) | IFIHC-P1:100-500 |
Frequently asked questions
Which applications is STAT5A Recombinant Antibody (bsm-60899R) validated for, and at what dilution?
bsm-60899R is validated for IHC-P(IHC-P) (1:100-500); IHC-F(IHC-F) (1:100-500); IF(IHC-P)(IF(IHC-P)) (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does STAT5A Recombinant Antibody (bsm-60899R) react with?
Tested reactivity: Human.
How should bsm-60899R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise STAT5A Recombinant Antibody (bsm-60899R)?
KLH conjugated synthetic peptide derived from human STAT5