beta Arrestin 1 Recombinant Antibody, PE Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61185r-pe-100uL |
| Product Name | beta Arrestin 1 Recombinant Antibody, PE Conjugated |
| Applications |
WB
FCM
IF(IHC-P)
IF(ICC)
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | PE |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human beta Arrestin 1 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 408 |
| Swiss Prot | P49407 |
| Subcellular location | Cytoplasm, Nucleus, Cell membrane |
| Synonyms | ARRB1; ARB1; ARR1; Arrestin beta 1; Beta arrestin 1. |
| Background | Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. |
| Application Dilution | |
| WB | 1:500-2000 |
| FCM | FCM1:50-100 |
| IF(IHC-P) | IFIHC-P1:100-500 |
| IF(ICC) | IFICC1:50-200 |
Frequently asked questions
Which applications is beta Arrestin 1 Recombinant Antibody, PE Conjugated (bsm-61185R-PE) validated for, and at what dilution?
bsm-61185R-PE is validated for WB(WB) (1:500-2000); FCM(FCM) (1:50-100); IF(IHC-P)(IF(IHC-P)) (1:100-500); IF(ICC)(IF(ICC)) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does beta Arrestin 1 Recombinant Antibody, PE Conjugated (bsm-61185R-PE) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-61185R-PE be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise beta Arrestin 1 Recombinant Antibody, PE Conjugated (bsm-61185R-PE)?
KLH conjugated synthetic peptide derived from human beta Arrestin 1
What are the excitation and emission wavelengths of the PE conjugate (bsm-61185R-PE)?
PE on bsm-61185R-PE: excitation / emission 496,564nm/578nm.