| Overview |
| bsm-61188r-rbitc-100ul |
| Hsc70 Recombinant Antibody, RBITC Conjugated |
| WB, FCM, IF(IHC-P), IF(ICC) |
| Human, Mouse, Rat |
| Specifications |
| RBITC |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Hsc70 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 3312 |
| P11142 |
| Cytoplasm, Nucleus, Cell membrane |
| Heat shock cognate 71 kDa protein; HS7C; HSP73; HSP7C; HSPA10; HSPA8. |
| Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, chaperone-mediated autophagy, activation of proteolysis of misfolded proteins, formation and dissociation of protein complexes, and antigen presentation. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. |
| Application Dilution |
| WB |
1:500-2000 |
| FCM |
FCM1:50-100 |
| IF(IHC-P) |
IFIHC-P1:50-200 |
| IF(ICC) |
IFICC1:50-200 |