Phospho-beta Arrestin 1 (Ser412) Recombinant Antibody, Biotin Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61196r-biotin |
| Product Name | Phospho-beta Arrestin 1 (Ser412) Recombinant Antibody, Biotin Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human beta Arrestin 1 around the phosphorylation site of S412 |
| Modification Site | Ser412 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 408 |
| Swiss Prot | P49407 |
| Subcellular location | Cytoplasm, Nucleus, Cell membrane |
| Synonyms | ARB1; ARR1; ARRB1; Arrestin 2; Arrestin beta 1. |
| Background | Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. |
| Application Dilution | |
| WB | 1:500-2000 |
Frequently asked questions
Which applications is Phospho-beta Arrestin 1 (Ser412) Recombinant Antibody, Biotin Conjugated (bsm-61196R-Biotin) validated for, and at what dilution?
bsm-61196R-Biotin is validated for WB(WB) (1:500-2000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Phospho-beta Arrestin 1 (Ser412) Recombinant Antibody, Biotin Conjugated (bsm-61196R-Biotin) react with?
Tested reactivity: Human.
How should bsm-61196R-Biotin be stored?
Store at -20°C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Phospho-beta Arrestin 1 (Ser412) Recombinant Antibody, Biotin Conjugated (bsm-61196R-Biotin)?
KLH conjugated synthetic peptide derived from human beta Arrestin 1 around the phosphorylation site of S412