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Lamin B Receptor Recombinant Antibody, PE Conjugated

Applications

  • FCM
  • IF(IHC-P)

Reactivity

  • Human
  • Rat
Overview
Catalog # bsm-61224r-pe-100uL
Product Name Lamin B Receptor Recombinant Antibody, PE Conjugated
Applications
FCM IF(IHC-P)
Reactivity Human, Rat
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Lamin B Receptor
Clonality Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 3930
Swiss Prot Q14739
Subcellular location Cytoplasm, Nucleus, Cell membrane
Synonyms PHA; LMN2R; TDRD18; DHCR14B; LBR.
Background Plays a critical role in myeloid cell cholesterol biosynthesis which is essential to both myeloid cell growth and functional maturation .Mediates the activation of NADPH oxidases, perhaps by maintaining critical levels of cholesterol required for membrane lipid raft formation during neutrophil differentiation.Anchors the lamina and the heterochromatin to the inner nuclear membrane.
Application Dilution
FCM 1:50-100
IF(IHC-P) IFIHC-P1:50-200

Frequently asked questions

Which applications is Lamin B Receptor Recombinant Antibody, PE Conjugated (bsm-61224R-PE) validated for, and at what dilution?

bsm-61224R-PE is validated for FCM(FCM) (1:50-100); IF(IHC-P)(IF(IHC-P)) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does Lamin B Receptor Recombinant Antibody, PE Conjugated (bsm-61224R-PE) react with?

Tested reactivity: Human, Rat.

How should bsm-61224R-PE be stored?

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise Lamin B Receptor Recombinant Antibody, PE Conjugated (bsm-61224R-PE)?

KLH conjugated synthetic peptide derived from human Lamin B Receptor

What are the excitation and emission wavelengths of the PE conjugate (bsm-61224R-PE)?

PE on bsm-61224R-PE: excitation / emission 496,564nm/578nm.