Acetyl CoA carboxylase Recombinant Antibody, Biotin Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61228r-biotin |
| Product Name | Acetyl CoA carboxylase Recombinant Antibody, Biotin Conjugated |
| Applications |
WB
IHC-P
IHC-F
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Acetyl CoA carboxylase |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 32 |
| Swiss Prot | O00763 |
| Subcellular location | Cell membrane |
| Synonyms | ACAC; ACACA; ACACB; ACC; ACC-alpha; ACC1; ACC2; ACCA; ACCB; Acetyl-CoA carboxylase 1; Biotin carboxylase. |
| Background | ACC1 a subunit of acetyl-CoA carboxylase (ACC), a multifunctional enzyme system. Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Acetyl-CoA carboxylase (ACC) catalyzes the pivotal step of the fatty acid synthesis pathway. The 265 kDa ACCŚÁ (ACC1) is the predominant isoform found in liver, adipocytes, and mammary gland, while the 280 kDa ACCŚÂ (ACC2) is the major isoform in skeletal muscle and heart. |
| Application Dilution | |
| WB | 1:500-2000 |
| IHC-P | IHC-P1:200-800 |
| IHC-F | IHC-F1:200-800 |