ERR-alpha Recombinant Antibody, AbBy Fluor-488 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61241r-bf488 |
| Product Name | ERR-alpha Recombinant Antibody, AbBy Fluor-488 Conjugated |
| Applications |
WB
FCM
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | AbBy Fluor-488 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human ERR alpha |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 2101 |
| Swiss Prot | P11474 |
| Subcellular location | Nucleus |
| Synonyms | ESRRA; ERRa; ERR1; HERR1; NR3B1; Steroid hormone receptor ERR1; ERR-alpha; ERRalpha; ESRL1; Estrogen receptor-like 1; Estrogen-related receptor alpha. |
| Background | Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle. |
| Application Dilution | |
| WB | 1:500-2000 |
| FCM | FCM1:50-100 |
Frequently asked questions
Which applications is ERR-alpha Recombinant Antibody, AbBy Fluor-488 Conjugated (bsm-61241R-BF488) validated for, and at what dilution?
bsm-61241R-BF488 is validated for WB(WB) (1:500-2000); FCM(FCM) (1:50-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does ERR-alpha Recombinant Antibody, AbBy Fluor-488 Conjugated (bsm-61241R-BF488) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-61241R-BF488 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ERR-alpha Recombinant Antibody, AbBy Fluor-488 Conjugated (bsm-61241R-BF488)?
KLH conjugated synthetic peptide derived from human ERR alpha
What are the excitation and emission wavelengths of the AbBy Fluor-488 conjugate (bsm-61241R-BF488)?
AbBy Fluor-488 on bsm-61241R-BF488: excitation / emission 499nm/519nm.
