IRAKM Recombinant Antibody, Biotin Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61264r-biotin |
| Product Name | IRAKM Recombinant Antibody, Biotin Conjugated |
| Applications |
WB
IP
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human IRAK3 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 11213 |
| Swiss Prot | Q9Y616 |
| Subcellular location | Cytoplasm |
| Synonyms | ASRT5; FLJ13601; IL-1 receptor-associated kinase M; Interleukin-1 receptor-associated kinase 3; interleukin-1 receptor-associated kinase M; IRAK-3; IRAK-M; IRAK3; IRAKM. |
| Background | Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors.Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.Upon IL33-induced lung inflammation, positively regulates expression of IL6, CSF3, CXCL2 and CCL5 mRNAs in dendritic cells. |
| Application Dilution | |
| WB | 1:300-5000 |
| IP | 1-2ug |
Frequently asked questions
Which applications is IRAKM Recombinant Antibody, Biotin Conjugated (bsm-61264R-Biotin) validated for, and at what dilution?
bsm-61264R-Biotin is validated for WB (1:300-5000); IP (1-2ug). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does IRAKM Recombinant Antibody, Biotin Conjugated (bsm-61264R-Biotin) react with?
Tested reactivity: Human.
How should bsm-61264R-Biotin be stored?
Store at -20°C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise IRAKM Recombinant Antibody, Biotin Conjugated (bsm-61264R-Biotin)?
KLH conjugated synthetic peptide derived from human IRAK3