Cyclooxygenase 1 Recombinant Antibody, APC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61288r-apc-100uL |
| Product Name | Cyclooxygenase 1 Recombinant Antibody, APC Conjugated |
| Applications |
WB
IF(IHC-P)
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | APC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human COX 1 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 5742 |
| Swiss Prot | P23219 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | COX-1; COX1; COX3; Cyclooxygenase-1; PCOX1; PGG/HS; PGH synthase 1; PGH1; PGHS1; PHS1; Prostaglandin G/H synthase 1; Prostaglandin H2 synthase 1; PTGHS; PTGS1. |
| Background | Dual cyclooxygenase and peroxidase that plays an important role in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate ((5Z,8Z,11Z,14Z)-eicosatetraenoate, AA, C20:4(n-6)), with a particular role in the inflammatory response. The cyclooxygenase activity oxygenates AA to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and the peroxidase activity reduces PGG2 to the hydroxy endoperoxide prostaglandin H2 (PGH2), the precursor of all 2-series prostaglandins and thromboxanes. |
| Application Dilution | |
| WB | 1:500-2000 |
| IF(IHC-P) | IFIHC-P1:50-200 |
Frequently asked questions
Which applications is Cyclooxygenase 1 Recombinant Antibody, APC Conjugated (bsm-61288R-APC) validated for, and at what dilution?
bsm-61288R-APC is validated for WB(WB) (1:500-2000); IF(IHC-P)(IF(IHC-P)) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Cyclooxygenase 1 Recombinant Antibody, APC Conjugated (bsm-61288R-APC) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-61288R-APC be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Cyclooxygenase 1 Recombinant Antibody, APC Conjugated (bsm-61288R-APC)?
KLH conjugated synthetic peptide derived from human COX 1
What are the excitation and emission wavelengths of the APC conjugate (bsm-61288R-APC)?
APC on bsm-61288R-APC: excitation / emission 650nm/660nm.