FANCD2 Recombinant Antibody

$25 ug total protein per lane of various lysates (see on figure) probed with FANCD2 monoclonal antibody, unconjugated (bsm-61302R) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.$

25 ug total protein per lane of various lysates (see on figure) probed with FANCD2 monoclonal antibody, unconjugated (bsm-61302R) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

Applications

WB
IP
ICC/IF

Reactivity

Human

Overview
Catalog #	bsm-61302r-TR
Product Name	FANCD2 Recombinant Antibody
Applications	WB, IP, ICC/IF
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human FANCD2
Clonality	Recombinant
Isotype	IgG
Concentration	Lot dependent
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Storage Condition	Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	2177
Swiss Prot	Q9BXW9
Subcellular location	Nucleus
Synonyms	FA D2; FA4; FAC D2; FACD 2; FACD; FACD2; FAD; FAD2; FANCD 2; FANCD; FANCD2; Fanconi anemia group D2 protein; FLJ23826; Protein FACD2; Type 4 Fanconi pancytopenia.
Background	Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress.
Application Dilution
WB	1:300-5000
IP	1-2ug
ICC/IF	1:50-100