FANCD2 Recombinant Antibody, Cy3 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61302r-cy3-100uL |
| Product Name | FANCD2 Recombinant Antibody, Cy3 Conjugated |
| Applications |
WB
IF(ICC)
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Cy3 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human FANCD2 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 2177 |
| Swiss Prot | Q9BXW9 |
| Subcellular location | Nucleus |
| Synonyms | FA D2; FA4; FAC D2; FACD 2; FACD; FACD2; FAD; FAD2; FANCD 2; FANCD; FANCD2; Fanconi anemia group D2 protein; FLJ23826; Protein FACD2; Type 4 Fanconi pancytopenia. |
| Background | Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. |
| Application Dilution | |
| WB | 1:500-2000 |
| IF(ICC) | IFICC1:50-200 |
Frequently asked questions
Which applications is FANCD2 Recombinant Antibody, Cy3 Conjugated (bsm-61302R-Cy3) validated for, and at what dilution?
bsm-61302R-Cy3 is validated for WB(WB) (1:500-2000); IF(ICC)(IF(ICC)) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does FANCD2 Recombinant Antibody, Cy3 Conjugated (bsm-61302R-Cy3) react with?
Tested reactivity: Human.
How should bsm-61302R-Cy3 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise FANCD2 Recombinant Antibody, Cy3 Conjugated (bsm-61302R-Cy3)?
KLH conjugated synthetic peptide derived from human FANCD2
What are the excitation and emission wavelengths of the Cy3 conjugate (bsm-61302R-Cy3)?
Cy3 on bsm-61302R-Cy3: excitation / emission 512,550nm/570,615nm.