| Overview |
| bsm-61356r-biotin-100ul |
| Caspase 14 Recombinant Antibody, Biotin Conjugated |
| WB, IHC-P, IHC-F, IP |
| Human |
| Mouse, Rat |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Caspase 14 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 23581 |
| P31944 |
| Cytoplasm |
| CASP14; Caspase-14; Caspase 14; MICE; CASP-14. |
| Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum.Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin.In vitro has a preference for the substrate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IP |
1-2ug |