NUMB Recombinant Antibody, AbBy Fluor-647 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61410r-bf647 |
| Product Name | NUMB Recombinant Antibody, AbBy Fluor-647 Conjugated |
| Applications |
WB
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | AbBy Fluor-647 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human NUMB |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 8650 |
| Swiss Prot | P49757 |
| Subcellular location | Cell membrane |
| Synonyms | c14_5527; h Numb; Numb; Numb homolog; S171. |
| Background | Numb acts as a negative regulator of Notch signaling by promoting ubiquitination and degradation of Notch. The protein is asymmetrically segregated into one daughter cell during cell division, producing two daughter cells with different responses to Notch signaling and different cell fates. The localization of Numb can also be regulated by G-protein coupled receptor (GPCR) and PKC signaling. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is NUMB Recombinant Antibody, AbBy Fluor-647 Conjugated (bsm-61410R-BF647) validated for, and at what dilution?
bsm-61410R-BF647 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does NUMB Recombinant Antibody, AbBy Fluor-647 Conjugated (bsm-61410R-BF647) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-61410R-BF647 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise NUMB Recombinant Antibody, AbBy Fluor-647 Conjugated (bsm-61410R-BF647)?
KLH conjugated synthetic peptide derived from human NUMB
What are the excitation and emission wavelengths of the AbBy Fluor-647 conjugate (bsm-61410R-BF647)?
AbBy Fluor-647 on bsm-61410R-BF647: excitation / emission 650nm/665nm.