| Overview |
| bsm-61443r-biotin-100ul |
| Noxa Recombinant Antibody, Biotin Conjugated |
| WB |
| Human |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human PMAIP1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 5366 |
| Q13794 |
| Cytoplasm |
| APR; ATL-derived; NOXA; Pmaip1; Protein Noxa. |
| Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. |
| Application Dilution |
| WB |
1:300-5000 |
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