Noxa Recombinant Antibody, HRP Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61443r-hrp |
| Product Name | Noxa Recombinant Antibody, HRP Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | HRP |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human PMAIP1 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 5366 |
| Swiss Prot | Q13794 |
| Subcellular location | Cytoplasm |
| Synonyms | APR; ATL-derived; NOXA; Pmaip1; Protein Noxa. |
| Background | Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. |
| Application Dilution | |
| WB | 1:300-5000 |