RAC1/2/3 Recombinant Antibody, PBS Only Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61458r-pbs-only-100ul |
| Product Name | RAC1/2/3 Recombinant Antibody, PBS Only Conjugated |
| Applications | WB |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | PBS Only |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Rac1 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | PBS (pH=7.4) |
| Storage Condition | Store at 4°C for 12 months. |
| Target | |
| Gene ID | 5879 |
| Swiss Prot | P63000,P15153,P60763 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | Cell migration-inducing gene 5 protein; EN-7; GX; p21-Rac1; p21-Rac2; p21-Rac3; RAC1; RAC2; RAC3; TC25. |
| Background | In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development. GTP binding stimulates the activity of Rac/Cdc42, and the hydrolysis of GTP to GDP through the protein's intrinsic GTPase activity, rendering it inactive. |
| Application Dilution | |
| WB | 1:500-2000 |