FRS2 Recombinant Antibody, Biotin Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61526r-biotin |
| Product Name | FRS2 Recombinant Antibody, Biotin Conjugated |
| Applications |
WB
IP
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human FGFR substrate 2 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 10818 |
| Swiss Prot | Q8WU20 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | FGFR signaling adaptor SNT; FGFR substrate 2; FRS2; FRS2A; FRS2 alpha; SNT; SNT1; Suc 1. |
| Background | Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. |
| Application Dilution | |
| WB | 1:500-2000 |
| IP | IP1:20-50 |
Frequently asked questions
Which applications is FRS2 Recombinant Antibody, Biotin Conjugated (bsm-61526R-Biotin) validated for, and at what dilution?
bsm-61526R-Biotin is validated for WB(WB) (1:500-2000); IP(IP) (1:20-50). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does FRS2 Recombinant Antibody, Biotin Conjugated (bsm-61526R-Biotin) react with?
Tested reactivity: Human.
How should bsm-61526R-Biotin be stored?
Store at -20°C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise FRS2 Recombinant Antibody, Biotin Conjugated (bsm-61526R-Biotin)?
KLH conjugated synthetic peptide derived from human FGFR substrate 2