| Overview |
| bsm-61566r-pbs-only-100ul |
| CYP3A4 Recombinant Antibody, PBS Only Conjugated |
| WB, IHC-P, IHC-F, IF(IHC-P), IP |
| Human |
| Specifications |
| PBS Only |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Cytochrome P450 3A4 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 1576 |
| P08684 |
| Cytoplasm, Cell membrane |
| CYP3A4; CYPIIIA3; CYPIIIA4; Cytochrome P450 3A3; Cytochrome P450 HLp; Cytochrome P450 NF-25; Cytochrome P450-PCN1; Nifedipine oxidase. |
| A cytochrome P450 monooxygenase involved in the metabolism of sterols, steroid hormones, retinoids and fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. |
| Application Dilution |
| WB |
1:500-2000 |
| IHC-P |
IHC-P1:100-500 |
| IHC-F |
IHC-F1:100-500 |
| IF(IHC-P) |
IFIHC-P1:100-500 |
| IP |
IP1:20-50 |
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