| Overview |
| bsm-61576r-bf647-100ul |
| RASSF1A Recombinant Antibody, AbBy Fluor-647 Conjugated |
| IF |
| Human |
| Specifications |
| AbBy Fluor-647 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human RASSF1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 11186 |
| Q9NS23 |
| Cytoplasm, Nucleus |
| NORE2A |
| Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression. |
| Application Dilution |
| IF |
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