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RASSF1A Recombinant Antibody, PBS Only Conjugated

Applications

  • IHC-P
  • IHC-F
  • IF(IHC-P)

Reactivity

  • Human
Overview
Catalog # bsm-61576r-pbs-only-100ul
Product Name RASSF1A Recombinant Antibody, PBS Only Conjugated
Applications IHC-P, IHC-F, IF(IHC-P)
Reactivity Human
Specifications
Conjugation PBS Only
Host Rabbit
Source KLH conjugated synthetic peptide derived from human RASSF1
Clonality Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer PBS (pH=7.4)
Storage Condition Store at 4°C for 12 months.
Target
Gene ID 11186
Swiss Prot Q9NS23
Subcellular location Cytoplasm, Nucleus
Synonyms NORE2A
Background Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression.
Application Dilution
IHC-P 1:50-200
IHC-F IHC-F1:50-200
IF(IHC-P) IFIHC-P1:50-200