| Overview |
| bsm-61613r-biotin-100ul |
| CCBR1 Recombinant Antibody, Biotin Conjugated |
| WB, IP |
| Human, Mouse, Rat |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human xCT |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 23657 |
| Q9UPY5 |
| Cell membrane |
| CCBR1; Cysteine/glutamate transporter; SLC7A11; solute carrier family 7; xCT. |
| Heterodimer with SLC3A2, that functions as an antiporter by mediating the exchange of extracellular anionic L-cystine and intracellular L-glutamate across the cellular plasma membrane.Provides L-cystine for the maintenance of the redox balance between extracellular L-cystine and L-cysteine and for the maintenance of the intracellular levels of glutathione that is essential for cells protection from oxidative stress. |
| Application Dilution |
| WB |
1:300-5000 |
| IP |
1-2ug |