| Overview |
| bsm-61646r-pbs-only-100ul |
| CD207 Recombinant Antibody, PBS Only Conjugated |
| IHC-P, IHC-F, IF(IHC-P) |
| Human |
| Specifications |
| PBS Only |
| Rabbit |
| KLH conjugated synthetic peptide derived from human CD207 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 50489 |
| Q9UJ71 |
| Cell membrane |
| CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CLEC4K; Langerhans cell specific c type lectin; Langerin. |
| Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. |
| Application Dilution |
| IHC-P |
1:100-500 |
| IHC-F |
IHC-F1:100-500 |
| IF(IHC-P) |
IFIHC-P1:100-500 |