FADD Recombinant Antibody, APC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61661r-apc |
| Product Name | FADD Recombinant Antibody, APC Conjugated |
| Applications |
WB
FCM
IF(IHC-P)
|
| Reactivity | Mouse |
| Specifications | |
| Conjugation | APC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from mouse Fadd |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 14082 |
| Swiss Prot | Q61160 |
| Subcellular location | Cytoplasm |
| Synonyms | FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1. |
| Background | Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. |
| Application Dilution | |
| WB | 1:500-2000 |
| FCM | FCM1:50-100 |
| IF(IHC-P) | IFIHC-P1:50-200 |
Frequently asked questions
Which applications is FADD Recombinant Antibody, APC Conjugated (bsm-61661R-APC) validated for, and at what dilution?
bsm-61661R-APC is validated for WB(WB) (1:500-2000); FCM(FCM) (1:50-100); IF(IHC-P)(IF(IHC-P)) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does FADD Recombinant Antibody, APC Conjugated (bsm-61661R-APC) react with?
Tested reactivity: Mouse.
How should bsm-61661R-APC be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise FADD Recombinant Antibody, APC Conjugated (bsm-61661R-APC)?
KLH conjugated synthetic peptide derived from mouse Fadd
What are the excitation and emission wavelengths of the APC conjugate (bsm-61661R-APC)?
APC on bsm-61661R-APC: excitation / emission 650nm/660nm.