TRPM7 Recombinant Monoclonal Antibody, PE-Cy3 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61679r-pe-cy3 |
| Product Name | TRPM7 Recombinant Monoclonal Antibody, PE-Cy3 Conjugated |
| Applications |
WB
FCM
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | PE-Cy3 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human TRPM7 |
| Clonality | Monoclonal |
| Clone # | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 54822 |
| Swiss Prot | Q96QT4 |
| Subcellular location | Cell membrane |
| Synonyms | ALSPDC; CHAK; CHAK1; LTrpC7; TRPM7. |
| Background | Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium.Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is TRPM7 Recombinant Monoclonal Antibody, PE-Cy3 Conjugated (bsm-61679R-PE-Cy3) validated for, and at what dilution?
bsm-61679R-PE-Cy3 is validated for WB (1:300-5000); FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does TRPM7 Recombinant Monoclonal Antibody, PE-Cy3 Conjugated (bsm-61679R-PE-Cy3) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-61679R-PE-Cy3 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise TRPM7 Recombinant Monoclonal Antibody, PE-Cy3 Conjugated (bsm-61679R-PE-Cy3)?
KLH conjugated synthetic peptide derived from human TRPM7
What are the excitation and emission wavelengths of the PE-Cy3 conjugate (bsm-61679R-PE-Cy3)?
PE-Cy3 on bsm-61679R-PE-Cy3: excitation / emission 488nmn/578nm.