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KSR1 Recombinant Monoclonal Antibody, PE-Cy3 Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Human
  • Mouse
Overview
Catalog # bsm-61694r-pe-cy3
Product Name KSR1 Recombinant Monoclonal Antibody, PE-Cy3 Conjugated
Applications WB, FCM
Reactivity Human, Mouse
Specifications
Conjugation PE-Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from human KSR1
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 8844
Swiss Prot Q8IVT5
Subcellular location Cytoplasm, Cell membrane
Synonyms BKSR1; dKsr; EK31; KSR; KSR1; RSU2; SR31.
Background Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases.Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2.
Application Dilution
WB 1:300-5000
FCM 1:20-100