DARC Recombinant Antibody, APC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61907r-apc-100uL |
| Product Name | DARC Recombinant Antibody, APC Conjugated |
| Applications |
IF(IHC-P)
|
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | APC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Atypical chemokine receptor 1 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 2532 |
| Swiss Prot | Q16570 |
| Subcellular location | Cell membrane |
| Synonyms | CCBP1; CD234; DARC; Dfy; FY; GPD; GpFy; WBCQ1. |
| Background | Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. |
| Application Dilution | |
| IF(IHC-P) | 1:100-500 |
Frequently asked questions
Which applications is DARC Recombinant Antibody, APC Conjugated (bsm-61907R-APC) validated for, and at what dilution?
bsm-61907R-APC is validated for IF(IHC-P)(IF(IHC-P)) (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does DARC Recombinant Antibody, APC Conjugated (bsm-61907R-APC) react with?
Tested reactivity: Human, Mouse.
How should bsm-61907R-APC be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise DARC Recombinant Antibody, APC Conjugated (bsm-61907R-APC)?
KLH conjugated synthetic peptide derived from human Atypical chemokine receptor 1
What are the excitation and emission wavelengths of the APC conjugate (bsm-61907R-APC)?
APC on bsm-61907R-APC: excitation / emission 650nm/660nm.