MIB1 Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61914r-100uL |
| Product Name | MIB1 Recombinant Antibody |
| Applications |
WB
ICC/IF
|
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human MIB1 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 57534 |
| Swiss Prot | Q86YT6 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | Dip1; LVNC7; MIB; mib1; ZZANK2; ZZZ6. |
| Background | E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis. |
| Application Dilution | |
| WB | 1:1000-1:2000 |
| ICC/IF | 1:50-1:200 |
Frequently asked questions
Which applications is MIB1 Recombinant Antibody (bsm-61914R) validated for, and at what dilution?
bsm-61914R is validated for WB (1:1000-1:2000); ICC/IF (1:50-1:200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does MIB1 Recombinant Antibody (bsm-61914R) react with?
Tested reactivity: Human, Mouse.
How should bsm-61914R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
What immunogen was used to raise MIB1 Recombinant Antibody (bsm-61914R)?
KLH conjugated synthetic peptide derived from human MIB1