| Overview |
| bsm-61954r |
| CD112 Recombinant Antibody |
| WB, IP, Flow-Cyt, ICC/IF |
| Human, Mouse, Rat |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Nectin 2 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 5819 |
| Q92692 |
| HVEB; PRR2; CD112; PVRR2. |
| Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. |
| Application Dilution |
| WB |
1:300-5000 |
| IP |
FCM1:20-100 |
| Flow-Cyt |
IFICC1:50-200 |
| ICC/IF |
IP1-2ug |
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