PEN2 Recombinant Antibody, Cy7 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-61979r-cy7-100uL |
| Product Name | PEN2 Recombinant Antibody, Cy7 Conjugated |
| Applications |
WB
FCM
IF(IHC-P)
IF(ICC)
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Cy7 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human PEN 2 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 55851 |
| Swiss Prot | Q9NZ42 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | PEN 2; PSEN2; psenen. |
| Background | Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP.The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels (Probable). PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity. |
| Application Dilution | |
| WB | 1:500-2000 |
| FCM | FCM1:50-100 |
| IF(IHC-P) | IFIHC-P1:100-200 |
| IF(ICC) | IFICC1:50-200 |
Frequently asked questions
Which applications is PEN2 Recombinant Antibody, Cy7 Conjugated (bsm-61979R-Cy7) validated for, and at what dilution?
bsm-61979R-Cy7 is validated for WB(WB) (1:500-2000); FCM(FCM) (1:50-100); IF(IHC-P)(IF(IHC-P)) (1:100-200); IF(ICC)(IF(ICC)) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does PEN2 Recombinant Antibody, Cy7 Conjugated (bsm-61979R-Cy7) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-61979R-Cy7 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise PEN2 Recombinant Antibody, Cy7 Conjugated (bsm-61979R-Cy7)?
KLH conjugated synthetic peptide derived from human PEN 2
What are the excitation and emission wavelengths of the Cy7 conjugate (bsm-61979R-Cy7)?
Cy7 on bsm-61979R-Cy7: excitation / emission 743nm/767nm.