Niemann Pick C1 Like 1 Recombinant Antibody, AbBy Fluor-405 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-62028r-bf405 |
| Product Name | Niemann Pick C1 Like 1 Recombinant Antibody, AbBy Fluor-405 Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | AbBy Fluor-405 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human NPC1L1 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 29881 |
| Swiss Prot | Q9UHC9 |
| Subcellular location | Cell membrane |
| Synonyms | NPC1 LIKE 1; NPC1L1. |
| Background | Plays a major role in cholesterol homeostasis.Critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte.Involved in plant sterol absorption, it transports sitosterol, although at lower rates than cholesterol.Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption and is approved for the treatment of hypercholesterolemia. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is Niemann Pick C1 Like 1 Recombinant Antibody, AbBy Fluor-405 Conjugated (bsm-62028R-BF405) validated for, and at what dilution?
bsm-62028R-BF405 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Niemann Pick C1 Like 1 Recombinant Antibody, AbBy Fluor-405 Conjugated (bsm-62028R-BF405) react with?
Tested reactivity: Human.
How should bsm-62028R-BF405 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Niemann Pick C1 Like 1 Recombinant Antibody, AbBy Fluor-405 Conjugated (bsm-62028R-BF405)?
KLH conjugated synthetic peptide derived from human NPC1L1
What are the excitation and emission wavelengths of the AbBy Fluor-405 conjugate (bsm-62028R-BF405)?
AbBy Fluor-405 on bsm-62028R-BF405: excitation / emission 401nm/421nm.