| Overview |
| bsm-62038r-Cy5.5-100ul |
| EBF1 Recombinant Antibody, Cy5.5 Conjugated |
| WB |
| Human, Mouse |
| Specifications |
| Cy5.5 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human COE1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 1879 |
| Q9UH73 |
| Nucleus |
| COE1; EBF; Ebf1; O/E 1; OE1; OLF1. |
| Key pioneer transcription factor of B-cell specification and commitment.Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. |
| Application Dilution |
| WB |
1:300-5000 |
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