LGR6 Recombinant Antibody, Biotin Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-62179r-biotin |
| Product Name | LGR6 Recombinant Antibody, Biotin Conjugated |
| Applications |
WB
IHC-P
IHC-F
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human LGR6 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 59352 |
| Swiss Prot | Q9HBX8 |
| Subcellular location | Cell membrane |
| Synonyms | GPCR; Lgr6. |
| Background | Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor. |
| Application Dilution | |
| WB | 1:1000-2000 |
| IHC-P | IHC-P1:100-500 |
| IHC-F | IHC-F1:100-500 |
Frequently asked questions
Which applications is LGR6 Recombinant Antibody, Biotin Conjugated (bsm-62179R-Biotin) validated for, and at what dilution?
bsm-62179R-Biotin is validated for WB(WB) (1:1000-2000); IHC-P(IHC-P) (1:100-500); IHC-F(IHC-F) (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does LGR6 Recombinant Antibody, Biotin Conjugated (bsm-62179R-Biotin) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-62179R-Biotin be stored?
Store at -20°C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise LGR6 Recombinant Antibody, Biotin Conjugated (bsm-62179R-Biotin)?
KLH conjugated synthetic peptide derived from human LGR6