Phospho-GSK3 A/B (Tyr279/Tyr216) Recombinant Antibody, Cy7 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-62258r-cy7-100uL |
| Product Name | Phospho-GSK3 A/B (Tyr279/Tyr216) Recombinant Antibody, Cy7 Conjugated |
| Applications |
WB
IF
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Cy7 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human GSK3 alpha around the phosphorylation site of Y279 |
| Modification Site | Tyr279/Tyr216 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 2931 |
| Swiss Prot | P49840 |
| Subcellular location | Cytoplasm |
| Synonyms | Glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK3A. |
| Background | GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF | |
Frequently asked questions
Which applications is Phospho-GSK3 A/B (Tyr279/Tyr216) Recombinant Antibody, Cy7 Conjugated (bsm-62258R-Cy7) validated for, and at what dilution?
bsm-62258R-Cy7 is validated for WB (1:300-5000); IF. These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Phospho-GSK3 A/B (Tyr279/Tyr216) Recombinant Antibody, Cy7 Conjugated (bsm-62258R-Cy7) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-62258R-Cy7 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Phospho-GSK3 A/B (Tyr279/Tyr216) Recombinant Antibody, Cy7 Conjugated (bsm-62258R-Cy7)?
KLH conjugated synthetic peptide derived from human GSK3 alpha around the phosphorylation site of Y279
What are the excitation and emission wavelengths of the Cy7 conjugate (bsm-62258R-Cy7)?
Cy7 on bsm-62258R-Cy7: excitation / emission 743nm/767nm.