| Overview |
| bsm-62437r |
| NPC1 Recombinant Antibody |
| WB, IHC-P, IHC-F, IF, Flow-Cyt, ICC/IF |
| Human, Mouse, Rat |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Niemann pick C1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 4864 |
| O15118 |
| Niemann Pick C1 protein precursor; NPC; NPC1. |
| Intracellular cholesterol transporter which acts in concert with NPC2 and plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment.Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC-P |
FCM1:20-100 |
| IHC-F |
IHC-P1:200-400 |
| IF |
IHC-F1:100-500 |
| Flow-Cyt |
IFICC1:50-200 |
| ICC/IF |
IF |
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