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NPC1 Recombinant Antibody, Biotin Conjugated

Applications

  • WB
  • IHC-P
  • IHC-F

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-62437r-biotin-100ul
Product Name NPC1 Recombinant Antibody, Biotin Conjugated
Applications WB, IHC-P, IHC-F
Reactivity Human, Mouse, Rat
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Niemann pick C1
Clonality Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 4864
Swiss Prot O15118
Subcellular location Cytoplasm, Cell membrane
Synonyms Niemann Pick C1 protein precursor; NPC; NPC1.
Background Intracellular cholesterol transporter which acts in concert with NPC2 and plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment.Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500