RanBP3 Recombinant Antibody, HRP Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-62438r-hrp |
| Product Name | RanBP3 Recombinant Antibody, HRP Conjugated |
| Applications |
IHC-P
IHC-F
|
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | HRP |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human RanBP3 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 8498 |
| Swiss Prot | Q9H6Z4 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | Ran binding protein 3; RanBP3. |
| Background | Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. |
| Application Dilution | |
| IHC-P | 1:100-500 |
| IHC-F | IHC-F1:100-500 |