RanBP3 Recombinant Antibody, RBITC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-62438r-rbitc |
| Product Name | RanBP3 Recombinant Antibody, RBITC Conjugated |
| Applications |
FCM
IF(IHC-P)
IF(ICC)
|
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | RBITC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human RanBP3 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 8498 |
| Swiss Prot | Q9H6Z4 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | Ran binding protein 3; RanBP3. |
| Background | Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. |
| Application Dilution | |
| FCM | 1:50-100 |
| IF(IHC-P) | IFIHC-P1:100-500 |
| IF(ICC) | IFICC1:50-200 |
Frequently asked questions
Which applications is RanBP3 Recombinant Antibody, RBITC Conjugated (bsm-62438R-RBITC) validated for, and at what dilution?
bsm-62438R-RBITC is validated for FCM(FCM) (1:50-100); IF(IHC-P)(IF(IHC-P)) (1:100-500); IF(ICC)(IF(ICC)) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does RanBP3 Recombinant Antibody, RBITC Conjugated (bsm-62438R-RBITC) react with?
Tested reactivity: Human, Mouse.
How should bsm-62438R-RBITC be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise RanBP3 Recombinant Antibody, RBITC Conjugated (bsm-62438R-RBITC)?
KLH conjugated synthetic peptide derived from human RanBP3
What are the excitation and emission wavelengths of the RBITC conjugate (bsm-62438R-RBITC)?
RBITC on bsm-62438R-RBITC: excitation / emission 570nm/595nm.