GRK6 Recombinant Antibody, Cy3 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-62587r-cy3-100uL |
| Product Name | GRK6 Recombinant Antibody, Cy3 Conjugated |
| Applications |
WB
|
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | Cy3 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human GRK6 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 2870 |
| Swiss Prot | P43250 |
| Subcellular location | Cell membrane |
| Synonyms | G protein coupled receptor kinase 6; G protein coupled receptor kinase GRK6; G protein-coupled receptor kinase 6; Gprk6; Grk6. |
| Background | Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro). |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is GRK6 Recombinant Antibody, Cy3 Conjugated (bsm-62587R-Cy3) validated for, and at what dilution?
bsm-62587R-Cy3 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does GRK6 Recombinant Antibody, Cy3 Conjugated (bsm-62587R-Cy3) react with?
Tested reactivity: Human, Mouse.
How should bsm-62587R-Cy3 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise GRK6 Recombinant Antibody, Cy3 Conjugated (bsm-62587R-Cy3)?
KLH conjugated synthetic peptide derived from human GRK6
What are the excitation and emission wavelengths of the Cy3 conjugate (bsm-62587R-Cy3)?
Cy3 on bsm-62587R-Cy3: excitation / emission 512,550nm/570,615nm.