| Overview |
| bsm-62834r-biotin-100ul |
| Phospho-SHIP1 (Tyr1022) Recombinant Antibody, Biotin Conjugated |
| WB, IP |
| Human |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human INPP5D around the phosphorylation site of Y1022 |
| Tyr1022 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 3635 |
| Q92835 |
| Cytoplasm, Cell membrane |
| Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; SH2 domain-containing inositol 5'-phosphatase 1; SHIP-1; p150Ship; hp51CN; INPP5D; SHIP. |
| Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. |
| Application Dilution |
| WB |
1:300-5000 |
| IP |
1-2ug |