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Phospho-LRP6 (Ser1490) Recombinant Antibody

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bsm-62889r
Product Name Phospho-LRP6 (Ser1490) Recombinant Antibody
Applications
WB
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human LRP6 around the phosphorylation site of S1490
Modification Site Ser1490
Clonality Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Storage Condition Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 4040
Swiss Prot O75581
Subcellular location Cytoplasm, Cell membrane
Synonyms Low-density lipoprotein receptor-related protein 7.
Background Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation.
Application Dilution
WB 1:300-5000

Frequently asked questions

Which applications is Phospho-LRP6 (Ser1490) Recombinant Antibody (bsm-62889R) validated for, and at what dilution?

bsm-62889R is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does Phospho-LRP6 (Ser1490) Recombinant Antibody (bsm-62889R) react with?

Tested reactivity: Human.

How should bsm-62889R be stored?

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

What immunogen was used to raise Phospho-LRP6 (Ser1490) Recombinant Antibody (bsm-62889R)?

KLH conjugated synthetic peptide derived from human LRP6 around the phosphorylation site of S1490